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The Dark Side of Ozempic: Why Weight Loss Comes at a Cost

May 18, 2025 2:30 pm in by

A Surge in Popularity

Medications like Ozempic, Wegovy, and Mounjaro have exploded in popularity for weight loss, despite originally being designed to treat type 2 diabetes. These drugs mimic the GLP-1 hormone, which helps users feel full and reduce food intake. While many see impressive weight loss results, experts warn that the full picture isn’t quite so simple.

Photo illustration of the big three injectable prescription weight loss medicines. Ozempic, Victoza and Wegovy with weight scale. (Photo by: Michael Siluk/UCG/Universal Images Group via Getty Images)
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“Ozempic Face” and Rapid Weight Loss

One of the most visible side effects of these drugs is what’s now called “Ozempic Face” a gaunt, aged appearance that can result from rapid weight and muscle loss. Dr. Giles Yeo, a geneticist from the University of Cambridge, explains that this isn’t a unique drug-related phenomenon, but a byproduct of losing weight too quickly. “You can’t exercise a face,” he says, highlighting the need for exercise alongside medication to preserve muscle mass and appearance.

Not a Quick Fix

Dr. Yeo cautions against relying solely on these medications. While they work for many, most users will need to stay on them long-term or risk regaining the weight. This extended use is often underestimated by those hoping for a quick fix.

Serious Side Effects to Consider

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Beyond cosmetic concerns, Ozempic and similar drugs can cause gastrointestinal issues, nausea, and in some cases, acute pancreatitis. There are also increased risks for patients with heart conditions, diabetic eye disease, or those undergoing surgery. For these groups, the drugs may pose serious health threats.

“Gym and Jab”: A Balanced Approach

Dr. Yeo advocates for a realistic, responsible use of weight-loss drugs. He emphasizes a “gym and jab” approach using the medication as a stepping stone toward lasting lifestyle change, not a standalone solution.

As demand rises, experts urge users to stay informed, consult healthcare professionals, and view these drugs as tools, not miracles.

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